Mucosal Involvement in Bullous Pemphigoid Is Mostly Associated with Disease Severity and to Absence of Anti-BP230 Autoantibody
نویسندگان
چکیده
Citation: Clapé A, Muller C, Gatouillat G, Le Jan S, Barbe C, Pham B-N, Antonicelli F and Bernard P (2018) Mucosal Involvement in Bullous Pemphigoid Is Mostly Associated with Disease Severity and to Absence of Anti-BP230 Autoantibody. Front. Immunol. 9:479. doi: 10.3389/fimmu.2018.00479 Ariane Clapé1,2,3, Céline Muller1, Grégory Gatouillat1,3, Sébastien Le Jan1, Coralie Barbe4, Bach-Nga Pham1,3†, Frank Antonicelli1,5*† and Philippe Bernard1,2†
منابع مشابه
Usefulness of BP230 and BP180-NC16a enzyme-linked immunosorbent assays in the initial diagnosis of bullous pemphigoid: a retrospective study of 138 patients.
OBJECTIVE To investigate the diagnostic value of commercially available BP230 and BP180-NC16a enzyme-linked immunosorbent assays (ELISAs) in routine practice in patients with bullous pemphigoid (BP). DESIGN Single-center retrospective study. SETTING French academic dermatology department. PATIENTS The study population comprised 138 patients, who were admitted from January 1998 through Dec...
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Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another skin autoimmune disease characterized by anti-type VII collagen AAbs. We therefore evaluated the presence of anti-type VII collagen AAbs in the se...
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BACKGROUND Bullous pemphigoid (BP) is an autoimmune subepidermal bullous disease associated with autoantibodies against BP180 and BP230. Enzyme-linked immunosorbent assay (ELISA) is a sensitive tool for the detection of immunoglobulin G (IgG) anti-BP180 and anti-BP230 autoantibodies. OBJECTIVE The aim of this study was to evaluate the usefulness of ELISA for diagnosing and monitoring the dise...
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